Those who are intelligent know that everything is supplied by Krishna. So why not depend on Krishna only? Why so many other attempts? Therefore Krishna says,
bahu-sakha hy anantas ca
Vyavasayi means one who knows business particularly. Vyavasaya. Or one who knows confidently, “This is the cause; this is the effect.” Those who know that Krishna is the origin of everything are fixed up in Krishna. Vyavasayatmika buddhir ekeha. One. Just depend on Krishna. They who do not know this depend on so many things. Buddhi avyavasayina.
So, if we want to be Krishna conscious, we shall fix up our mind on Krishna. And how to become fixed up—that art will be given to you by the spiritual master. Therefore Visvanatha Cakravarti Thakura says in connection with the explanation of this verse, vyavasayatmika buddhih means to take the words of the spiritual master as one’s life and soul. That is vyavasaya . . . That is called vyavasayatmika buddhih. Visvanatha Cakravarti says that “Whatever I am ordered by the spiritual master, that is my life and soul. I don’t care for liberation. My only business is to serve my spiritual master.” And in the song we sing, Ye prasade pure sarva asa. Ye prasade means, “By his mercy, all our desires are fulfilled.” Ye prasade pure sarva asa.
So, this is our process, to depend on Krishna. “Depend” does not mean I shall remain idle. Depend means to work according to the direction of the shastra. Sadhu-sastra-guru-vakya, tinete kariya aikya [Srila Narottam dasa Thakura].
—Srila Prabhupada, talk on Srimad-Bhagavatam 1.16.24, July 14, 1974, Los Angeles