• Volunteer

    hare krsna.. dandavat pranam..


    Myelodysplasia or the MDSs are a heterogeneous group of hematologic disorders broadly
    characterized by cytopenias associated with a dysmorphic (or abnormal appearing) and
    usually cellular bone marrow, and by consequent ineffective blood cell production.

    Five entities were defined: refractory anemia (RA),
    refractory anemia with ringed sideroblasts (RARS), refractory anemia with excess blasts
    (RAEB), refractory anemia with excess blasts in transformation (RAEB-t), and chronic
    myelomonocytic leukemia (CMML).

    Anemia dominates the early course. Most symptomatic patients complain of the gradual
    onset of fatigue and weakness, dyspnea, and pallor, but at least one-half the patients are
    asymptomatic, and their MDS is discovered only incidentally on routine blood counts.
    Previous chemotherapy or radiation exposure is an important historic fact.

    The physical examination is remarkable for signs of anemia; approximately 20% of
    patients have splenomegaly. 

      since, you are having the mildest form of the disease, that means you are only may be having anemia..

    so, dont worry too much, just consult your physician and take guidance and follow them.. everything will be allright..


    • Hare Kirshna!

      Thank you for your time. I was anaemic and still am. When they did bone marrow on me, it was found that I was having MDS and there are genetic markers, it seems. Doctor told me that it is in mild form and I have been given injection Cresp 200 units once a week, so that my HB doesn't drop down. It used to before I took injection. He also told me that there is no treatment for MDS. I have also been diagnosed with spleen enlargement and liver enlargement. According to the liver biopsy, it was found that it was fatty liver and that it will go once the fat is reduced. Problem is I am getting very much tired(got 2 small kids and house to manage, so that may be the reason) and also, my BP keeps dropping down.


      I want to know what will be the worst case? Will mild MDS will increase to intense form? or it will stay like this forever? That's the reason I was asking for worst case.


      Please help me clear my doubt.


      your servant

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