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By material means, one cannot avoid the happiness and distress unique to his particular body. Each one of us is destined to enjoy and suffer a certain amount of happiness and distress. This we cannot change, as we are bound by the stringent laws of karma. The main purpose of life is to follow the instructions of the Supreme Personality of Godhead. It is such instructions that constitute one's religion or occupational duty. By this we can transcend the material modes.