The supreme occupation (dharma) for all humanity is that by which men can attain to loving devotional service unto the transcendent Lord. Such devotional service must be unmotivated and uninterrupted to completely satisfy the self.
In this statement, Śrī Sūta Gosvāmī answers the first question of the sages of Naimiṣāraṇya. The sages asked him to summarize the whole range of revealed scriptures and present the most essential part so that fallen people or the people in general might easily take it up. The Vedas prescribe two different types of occupation for the human being. One is called the pravṛtti-mārga, or the path of sense enjoyment, and the other is called the nivṛtti-mārga, or the path of renunciation. The path of enjoyment is inferior, and the path of sacrifice for the supreme cause is superior. The material existence of the living being is a diseased condition of actual life. Actual life is spiritual existence, or brahma-bhūta (SB 4.30.20) existence, where life is eternal, blissful and full of knowledge. Material existence is temporary, illusory and full of miseries. There is no happiness at all. There is just the futile attempt to get rid of the miseries, and temporary cessation of misery is falsely called happiness. Therefore, the path of progressive material enjoyment, which is temporary, miserable and illusory, is inferior. But devotional service to the Supreme Lord, which leads one to eternal, blissful and all-cognizant life, is called the superior quality of occupation. This is sometimes polluted when mixed with the inferior quality. For example, adoption of devotional service for material gain is certainly an obstruction to the progressive path of renunciation. Renunciation or abnegation for ultimate good is certainly a better occupation than enjoyment in the diseased condition of life. Such enjoyment only aggravates the symptoms of disease and increases its duration. Therefore devotional service to the Lord must be pure in quality, i.e., without the least desire for material enjoyment. One should, therefore, accept the superior quality of occupation in the form of the devotional service of the Lord without any tinge of unnecessary desire, fruitive action and philosophical speculation. This alone can lead one to perpetual solace in His service.
We have purposely denoted dharma as occupation because the root meaning of the word dharma is "that which sustains one's existence." A living being's sustenance of existence is to coordinate his activities with his eternal relation with the Supreme Lord Kṛṣṇa. Kṛṣṇa is the central pivot of living beings, and He is the all-attractive living entity or eternal form amongst all other living beings or eternal forms. Each and every living being has his eternal form in the spiritual existence, and Kṛṣṇa is the eternal attraction for all of them. Kṛṣṇa is the complete whole, and everything else is His part and parcel. The relation is one of the servant and the served. It is transcendental and is completely distinct from our experience in material existence. This relation of servant and the served is the most congenial form of intimacy. One can realize it as devotional service progresses. Everyone should engage himself in that transcendental loving service of the Lord, even in the present conditional state of material existence. That will gradually give one the clue to actual life and please him to complete satisfaction.
(Srimad Bhagavatam----1:2:6----purport).

Just like a child... Child is playing all day and doing mischief in the house, and... So he cannot be stopped mischief-doing. He must be given some engagement. If he's given some engagement, some playthings, and if his attention is diverted there, then he'll stop mischief-making in the house. Otherwise, idle brain, devil's workshop. He will go on, go on. So therefore we must have spiritual engagement. Simple understanding that "I am spirit soul" will not help me.
Brahma-bhūtaḥ prasannātmā (B.G.18:54). The brahma-bhūtaḥ stage, situation, is that "I am not matter; I am spirit." That's all right. But we have to sustain the spirit. How we can sustain?We can sustain when there is spiritual engagement. Otherwise, it is not possible. Otherwise, I may continue for some time, but there is chance of falling down because we have got this information and a practical experience also: great, great, I mean to say, yogis and jñānīs, they again come. We have some practical experience. Sometimes we find a person leaves all worldly engagements, leaves his family, gives up his family connection, becomes a renounced order, sannyāsī, and highest order, and then, after some time, he becomes engaged in opening hospitals and philanthropic work and in politics.
We have seen it. Oh, why? You have renounced the world. Why you are hospital-making business? Hospital-making business is there, going on by the government, by the state. You are not meant for making hospitals. You have to make hospital how people can get rid of this material body. That is spiritual activity. We also require to open hospitals. And what is that hospital? To cure this material disease, not this temporary disease. Again we may be attacked. The complete cure of material disea... That sort of hospital will be required. That hospital is this Kṛṣṇa consciousness society. If we take treatment under this Kṛṣṇa consciousness society, then we shall be cured of this material disease.
(Lecture on Bhagavad-Gita--4:37-40).

“When one gets a devotee's spiritual body, he can remember the transcendental qualities of Kṛṣṇa. Simply by being attracted to Kṛṣṇa's transcendental qualities, one becomes a pure devotee engaged in His service.
Śrīla Bhaktivinoda Ṭhākura has given the following summary of verses 107–111. Transcendentalists on the path of philosophical speculation can be divided into two categories—the pure worshipers of impersonal Brahman and those who wish to merge into the existence of impersonal Brahman. When one is fully absorbed in the thought that one is not different from the Supreme Absolute Truth, one is said to be a worshiper of the impersonal Brahman. The impersonal worshipers of Brahman can again be divided into three categories—(1) sādhakas, those who are nearing perfect execution of the process of Brahman realization; (2) those who are fully absorbed in meditation on Brahman; and (3) those who are on the brahma-bhūta (S.B.4:30:20) platform and have no relationship with material existence. Even though the worshiper of impersonal Brahman can be highly advanced, he cannot attain liberation without discharging devotional service. Anyone who has realized himself as spirit soul can engage in devotional service. This is the verdict of the Bhagavad-gītā (18.54):
brahma-bhūtaḥ prasannātmā na śocati na kāṅkṣati
samaḥ sarveṣu bhūteṣu mad-bhaktiṁ labhate parām
"One who is thus transcendentally situated at once realizes the Supreme Brahman and becomes fully joyful. He never laments or desires to have anything; he is equally disposed to every living entity. In that state he attains pure devotional service unto Me."
To attain the platform of pure devotional service, one has to become spiritually pure and attain the brahma-bhūta platform, which is beyond material anxiety and material discrimination. When one approaches pure devotional service after realizing Brahman, one becomes attracted by pure devotional service. At such a time, by rendering devotional service, one gets a spiritual body with purified senses.
sarvopādhi-vinirmuktaṁ tat-paratvena nirmalam
hṛṣīkeṇa hṛṣīkeśa-sevanaṁ bhaktir ucyate
(CC-2:19:170)
When one's senses are pure, one can render loving devotional service to Kṛṣṇa. A pure devotee can only remember Kṛṣṇa's transcendental qualities. Remembering them, he fully engages in the loving service of the Lord.
(Sri Caitanya Caritamrta----2:24:111----purport).

Caitanya Mahāprabhu begins from this brahma-bhūtaḥ stage. His teaching is completely on the spiritual platform. Therefore people misunderstand us. Because we are speaking from the spiritual platform everything, they cannot understand. It requires practice.
(Morning Walk---10th. November, 1975).