Śrīla Viśvanātha Cakravartī Ṭhākura says in this connection that one who has developed Kṛṣṇa consciousness and who exists in love with Kṛṣṇa is no longer subject to suffering and happiness under the laws of karma. Indeed, he is beyond karma. The Brahma-saṁhitā says, karmāṇi nirdahati kintu ca bhakti-bhājām: (Bs. 5.54) a devotee is free from the reactions of his karma because he has taken to devotional service. This same principle is confirmed in Bhagavad-gītā (14.26). Sa guṇān samatītyaitān brahma-bhūyāya kalpate: one who is engaged in devotional service has already been freed from the reactions of his material karma, and thus he immediately becomes brahma-bhūta (S.B.4:30:20), or transcendental.
(Srimad Bhagavatam-----6:17:17-----purport).

Everyone has a limited duration of life, but a devotee's lifetime can be extended by the mercy of the Supreme Lord, who is able to nullify the results of one's karma. Karmāṇi nirdahati kintu ca bhakti-bhājāṁ (Bs. 5.54). This is the statement of Brahma-saṁhitā (5.54). A devotee is not under the laws of karma. Therefore even a devotee's scheduled death can be avoided by the causeless mercy of the Supreme Lord. God protects the devotee even from the extreme danger of death.
(Srimad Bhagavatam-----7:10:29-----purport).

There are different kinds of welfare activities in this material world, but the supreme welfare activity is the spreading of Kṛṣṇa consciousness. Other welfare activities cannot be effective, for the laws of nature and the results of karma cannot be checked. It is by destiny, or the laws of karma, that one must suffer or enjoy. For instance, if one is given a court order, he must accept it, whether it brings suffering or profit. Similarly, everyone is under obligations to karma and it reactions. No one can change this.
(Srimad Bhagavatam-----8:7:44-----purport).

As a result of such activities, the performer is immediately recognized. Na ca tasmān manuṣyeṣu kaścin me priya-kṛttamaḥ (B.G.18:69). Such a devotee, because of full knowledge of the Supreme Personality of Godhead, is immediately transcendental, although he may superficially appear to be engaged in materialistic activities. The only distinction between materialistic activity and spiritual activity is that material activity is performed only to satisfy one's own senses whereas spiritual activity is meant to satisfy the transcendental senses of the Supreme Personality of Godhead. By spiritual activity everyone factually benefits, whereas by materialistic activity no one benefits and instead one becomes entangled in thelaws of karma.
(Srimad Bhagavatam-----8:9:29-----purport).

Those who engage in devotional service are unaffected by the results of their material activities. Otherwise, everyone, from the smallest microbe up to the King of heaven, Indra, is subject to the laws of karma. A pure devotee, being always engaged in the service of the Lord, is exempt from these laws.
(Srimad Bhagavatam-----9:12:15-----purport).

The Paramātmā, or Supersoul, the guide of the individual living beings, does not take part in fulfilling the desires of the living beings, but He arranges for their fulfillment by material nature. As soon as an individual soul becomes conscious of his eternal relationship with the Supersoul and looks only toward Him, he at once becomes free from the entanglements of material enjoyment. Christian philosophers who do not believe in the law of karma put forward the argument that it is absurd to say one must accept the results of past deeds of which he has no consciousness. A criminal is first reminded of his misdeeds by witnesses in a law court, and then he is punished. If death is complete forgetfulness, why should a person be punished for his past misdeeds? The conception of the Paramātmā is an invincible answer to these fallacious arguments. The Paramātmā is the witness of the past activities of the individual living being. A man may not remember what he has done in his childhood, but his father, who has seen him grow through different stages of development, certainly remembers. Similarly, the living being undergoes many changes of body through many lives, but the Supersoul is always with him and remembers all his activities, despite his evolution through different bodies.
(Sri Caitanya Caritamrta-----1:2:19-----purport).

"No one should become a spiritual master—nor a relative, father, mother, worshipable Deity or husband—if he cannot help a person escape the imminent path of death." Every living entity is wandering within the universe, subjected to the law of karma and transmigrating from one body to another and from one planet to another. Therefore the whole Vedic process is meant to save the wandering living entities from the clutches of māyā—birth, death, disease and old age. This means stopping the cycle of birth and death. This cycle can be stopped only if one worships Kṛṣṇa.
(Sri Caitanya Caritamrta-----2:3:181-----purport).

According to the law of karma, everyone is destined to suffer or enjoy according to a certain material standard, but the mercy of Lord Kṛṣṇa is so powerful that the Lord can change all the reactions of one's past karma, or fruitive activities. Lord Śrī Caitanya Mahāprabhu specifically drew attention to the mercy of Lord Kṛṣṇa. That mercy is more powerful than anything else, for it had saved Raghunātha dāsa from the strong bondage of materialistic life, which the Lord compared to a hole where people pass stool. Śrī Caitanya Mahāprabhu gave His verdict that those addicted to the materialistic way of life are like worms that are living in stool but cannot give it up. A gṛha-vrata, one who has decided to live in a comfortable home although it is actually miserable, is in a condemned position. Only the mercy of Kṛṣṇa can save one from such misery. Without Kṛṣṇa's mercy, one cannot get out of the filthy entanglement of materialistic life. The poor living entity cannot give up his materialistic position on his own; only when granted the special mercy of Kṛṣṇa can he give it up.
(Sri Caitanya Caritamrta-----1:6:193-----purport).

There are innumerable hellish engagements in the modern so-called civilization, and by the grace of the Lord's illusory energy people think these hellish engagements are a great fortune. Modern industrial factories fully equipped with up-to-date machines are so many Kumbhīpāka hells, and the organizers of these enterprises regard them as indispensable for the advancement of economic welfare. The mass of laborers exploited by the organizers directly experience the "welfare" conditions in these factories, but what the organizers do not know is that by the law of karma they will in due time become laborers in similar Kumbhīpāka hells.
(Mukunda-Mala-Stotra).

One may aspire to live for hundreds of years if he continuously goes on working in that way, for that sort of work will not bind him to the law of karma. There is no alternative to this way for man.
No one wants to die: everyone wants to live as long as he can drag on. This tendency is visible not only individually but also collectively in the community, society and nation. There is a hard struggle for life by all kinds of living entities, and the Vedas say that this is quite natural. The living being is eternal by nature, but due to his bondage in material existence he has to change his body over and over. This process is called transmigration of the soul or karma-bandhana, bondage by one's work. The living entity has to work for his livelihood because that is the law of material nature, and if he does not act according to his prescribed duties, he transgresses the law of nature and binds himself more and more to the cycle of birth and death in the many species of life.
(Sri Isopanishad----translation and purport).